Real-time analysis of initiation regulation systems during the progression of the reconstituted chromosomal replication cycle

Abstract Chromosome replication in Escherichia coli is primarily regulated at the initiation stage, where the DnaA protein activates replication at the chromosomal origin, oriC. Both DnaA and oriC undergo feedback regulation based on replication progression. Previously, we reconstituted the entire r...

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Detalhes bibliográficos
Principais autores: Koki Kanoh, Masayuki Su’etsugu
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2025-02-01
coleção:Scientific Reports
Assuntos:
Acesso em linha:https://doi.org/10.1038/s41598-025-88988-0