Crack the state of silence: Tune the depth of cellular quiescence for cancer therapy
The regulation of cellular quiescence underlies numerous physiopathological phenomena. We recently found that quiescence depth can be tuned as to adjust a dimmer switch, by altering the expression of genes in the Retinoblastoma (Rb)-E2f pathway. Reducing quiescence depth may wake dormant cancer cell...
| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Taylor & Francis Group
2018-01-01
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| coleção: | Molecular & Cellular Oncology |
| Assuntos: | |
| Acesso em linha: | http://dx.doi.org/10.1080/23723556.2017.1403531 |