Paclitaxel liposome, cisplatin and 5-fluorouracil-based induction chemotherapy followed by de-escalated intensity-modulated radiotherapy with concurrent cisplatin in stage IVA–IVB childhood nasopharyngeal carcinoma in endemic area: a phase II, single-arm trialResearch in context

Paclitaxel liposome, cisplatin and 5-fluorouracil-based induction chemotherapy followed by de-escalated intensity-modulated radiotherapy with concurrent cisplatin in stage IVA–IVB childhood nasopharyngeal carcinoma in endemic area: a phase II, single-arm trialResearch in context

Summary: Background: Previous studies demonstrated that induction chemotherapy (IC) followed by de-escalated chemoradiotherapy adapted to tumor response was effective in treating childhood nasopharyngeal carcinoma (NPC), but the toxicity profile of this treatment strategy, and whether childhood pat...

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Bibliographic Details
Main Authors: Dong-Hua Luo, Xiao-Yun Li, Shan-Shan Guo, Wan-Ping Guo, Li-Ting Liu, Hao-Yuan Mo, Ling Guo, Xiao-Fei Lv, Li-Zhi Liu, Ji-Bin Li, Qing Liu, Pan Wang, Xue-Song Sun, Sai-Lan Liu, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:The Lancet Regional Health. Western Pacific
Subjects:
Nasopharyngeal carcinoma
Children and adolescents
Chemoradiotherapy
Induction chemotherapy
Survival
Online Access:http://www.sciencedirect.com/science/article/pii/S2666606523002134

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http://www.sciencedirect.com/science/article/pii/S2666606523002134

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