Repeated stress exposure leads to structural synaptic instability prior to disorganization of hippocampal coding and impairments in learning

Abstract Stress exposure impairs brain structure and function, resulting in cognitive deficits and increased risk for psychiatric disorders such as depression, schizophrenia, anxiety and post-traumatic stress disorder. In particular, stress exposure affects function and structure of hippocampal CA1...

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Bibliographic Details
Main Authors: Alireza Chenani, Ghabiba Weston, Alessandro F. Ulivi, Tim P. Castello-Waldow, Rosa-Eva Huettl, Alon Chen, Alessio Attardo
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02107-5