Analysis of T cell repertoires of CD45RO CD4 T cells in cohorts of patients with bullous pemphigoid: A pilot study

Analysis of T cell repertoires of CD45RO CD4 T cells in cohorts of patients with bullous pemphigoid: A pilot study

Autoimmune diseases develop over years - starting from a subclinical phenotype to clinically manifest autoimmune disease. The factors that drive this transition are ill-defined. To predict the turning point towards clinical disease and to intervene in the progress of autoimmune-mediated dysfunction,...

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Bibliographic Details
Main Authors: Markus Niebuhr, Farbod Bahreini, Anke Fähnrich, Christina Bomholt, Katja Bieber, Enno Schmidt, Saleh Ibrahim, Christoph M. Hammers, Kathrin Kalies
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
naive and memory CD4 T cells
autoimmunity
skin diseases
T cell receptor
repertoire diversity
next generation sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1006941/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1006941/full

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