Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures

Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures

Abstract Parkinson’s disease (PD) is a multi-stage neurodegenerative disorder with largely unknown etiology. Recent findings have identified PD-associated autoimmune features including roles for T cells. To further characterize the role of T cells in PD, we performed RNA sequencing on PBMC and perip...

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Bibliographic Details
Main Authors: Rekha Dhanwani, João Rodrigues Lima-Junior, Ashu Sethi, John Pham, Gregory Williams, April Frazier, Yaqian Xu, Amy W. Amara, David G. Standaert, Jennifer G. Goldman, Irene Litvan, Roy N. Alcalay, Bjoern Peters, David Sulzer, Cecilia S. Lindestam Arlehamn, Alessandro Sette
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-022-00282-2

Internet

https://doi.org/10.1038/s41531-022-00282-2

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