The Critical Role Played by Mitochondrial MITF Serine 73 Phosphorylation in Immunologically Activated Mast Cells

The Critical Role Played by Mitochondrial MITF Serine 73 Phosphorylation in Immunologically Activated Mast Cells

In recent years, growing evidence has indicated the pivotal role of mitochondria in mast cell immunological activation. We have previously reported a decrease in degranulation and cytokine secretion following the inhibition of pyruvate dehydrogenase (PDH) either by CPI-613 (PDH inhibitor/anti-cancer...

Full description

Bibliographic Details
Main Authors: Lakshmi Bhargavi Paruchuru, Sharmila Govindaraj, Ehud Razin
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
allergy
mast cells
mitochondria
microphthalmia-associated transcription factor
pyruvate dehydrogenase
extracellular signal-regulated kinase
Online Access:https://www.mdpi.com/2073-4409/11/3/589

Internet

https://www.mdpi.com/2073-4409/11/3/589

Similar Items