Intestinal PTGS2 mRNA levels, PTGS2 gene polymorphisms, and colorectal carcinogenesis.

Intestinal PTGS2 mRNA levels, PTGS2 gene polymorphisms, and colorectal carcinogenesis.

Inflammation is a major risk factor for development of colorectal cancer (CRC). Prostaglandin synthase cyclooxygenase-2 (COX-2) encoded by the PTGS2 gene is the rate limiting enzyme in prostaglandin synthesis and therefore plays a distinct role as regulator of inflammation.PTGS2 mRNA levels were det...

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Bibliographic Details
Main Authors: Lotte K Vogel, Mona Sæbø, Helle Høyer, Tine Iskov Kopp, Ulla Vogel, Sine Godiksen, Franz B Frenzel, Julian Hamfjord, Inger Marie Bowitz-Lothe, Egil Johnson, Elin H Kure, Vibeke Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4148233?pdf=render

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http://europepmc.org/articles/PMC4148233?pdf=render

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