Integrative bioinformatic analysis of p53 and pathway alterations in two different lung cancer subtypes

Integrative bioinformatic analysis of p53 and pathway alterations in two different lung cancer subtypes

Whether p53, either wild type (WT) or mutant, plays cell-specific or uniform role remains controversial. Using The Cancer Genome Atlas, we examined p53 in the lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), two lung cancers with different cellular origins and frequent p53 mutatio...

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Bibliographic Details
Main Authors: Yun Zhang, Abie Williams-Villalobo, Jyotsna D. Godavarthi, Faith Shakoor, Shunbin Xiong, Bin Liu
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
p53
Lung adenocarcinoma
Lung squamous cell carcinoma
TCGA
Ingenuity pathway analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822002047

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http://www.sciencedirect.com/science/article/pii/S2405580822002047

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