Theoretical Study on the Copper-Catalyzed <i>ortho</i>-Selective C-H Functionalization of Naphthols with <i>α</i>-Phenyl-<i>α</i>-Diazoesters

Theoretical Study on the Copper-Catalyzed <i>ortho</i>-Selective C-H Functionalization of Naphthols with <i>α</i>-Phenyl-<i>α</i>-Diazoesters

The aromatic C(sp<sup>2</sup>)-H functionalization of unprotected naphthols with <i>α</i>-phenyl-<i>α</i>-diazoesters under mild conditions catalyzed by CuCl and CuCl<sub>2</sub> exhibits high efficiency and unique <i>ortho</i>-selectivity....

Full description

Bibliographic Details
Main Authors: Xiaoli Zhu, Xunshen Liu, Fei Xia, Lu Liu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molecules
Subjects:
copper catalysis
<i>ortho</i>-C(sp<sup>2</sup>)-H bond functionalization
naphthols
diazo compounds
metal carbene
density functional theory (DFT) calculations
Online Access:https://www.mdpi.com/1420-3049/28/4/1767

Internet

https://www.mdpi.com/1420-3049/28/4/1767

Similar Items