Hyaluronic Acid-Protein Conjugate Modified Iron-Based MOFs (MIL-101 (Fe)) for Efficient Therapy of Neuroblastoma: Molecular Simulation, Stability and Toxicity Studies

Hyaluronic Acid-Protein Conjugate Modified Iron-Based MOFs (MIL-101 (Fe)) for Efficient Therapy of Neuroblastoma: Molecular Simulation, Stability and Toxicity Studies

Iron-based metal-organic frameworks (MIL (101)) have recently gained attention in materials science for biomedical applications. In the present work, Iron-based MOF (MIL-101(Fe)) were coated with lactoferrin (Lf) conjugated with hyaluronic acid (HA) and investigated its potential for delivering 5-fl...

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Bibliographic Details
Main Authors: Ajinkya N. Nikam, Abhijeet Pandey, Shivanand H. Nannuri, Gasper Fernandes, Sanjay Kulkarni, Bharath Singh Padya, Sumit Birangal, Gautham G. Shenoy, Sajan D. George, Srinivas Mutalik
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Crystals
Subjects:
metal-organic framework (MOF)
MIL-101(Fe)
5-FU
lactoferrin
transferrin
hyaluronic acid
Online Access:https://www.mdpi.com/2073-4352/12/10/1484

Internet

https://www.mdpi.com/2073-4352/12/10/1484

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