3160 The Effects of Aging on the Rectal Mucosal CD4+ T cell Compartment and its Implications for HIV Transmission

OBJECTIVES/SPECIFIC AIMS: In the first aim, we will evaluate the proportion of highly HIV-susceptible memory CD4+ T cells present in the rectal mucosa, based on the proliferation status and expression of the HIV susceptibility markers, CCR5 and α4β7, between HIV-negative adolescent MSM and adult MSM...

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Bibliographic Details
Main Authors: Cassie Grimsley Ackerley, Praveen Kumar Amancha, Phillip M. Murray, Jasper Barnes, Colleen F. Kelley
Format: Article
Language:English
Published: Cambridge University Press 2019-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866119002644/type/journal_article