Advances in the prerequisite and consequence of STING downstream signalosomes
The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is an evolving DNA-sensing mechanism involved in innate immunity and pathogen defense that has been optimized while remaining conserved. Aside from recognizing pathogens through conserved motifs, these receptors also d...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2024-10-01
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Series: | Medical Review |
Subjects: | |
Online Access: | https://doi.org/10.1515/mr-2024-0016 |