Torch-eCpG: a fast and scalable eQTM mapper for thousands of molecular phenotypes with graphical processing units

Torch-eCpG: a fast and scalable eQTM mapper for thousands of molecular phenotypes with graphical processing units

Abstract Background Gene expression may be regulated by the DNA methylation of regulatory elements in cis, distal, and trans regions. One method to evaluate the relationship between DNA methylation and gene expression is the mapping of expression quantitative trait methylation (eQTM) loci (also call...

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Bibliographic Details
Main Authors: Kord M. Kober, Liam Berger, Ritu Roy, Adam Olshen
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Bioinformatics
Subjects:
DNA methylation
Gene expression
Transcriptional regulation
Expression quantitative trait methylation
eQTM
eCpG
Online Access:https://doi.org/10.1186/s12859-024-05670-4

Internet

https://doi.org/10.1186/s12859-024-05670-4

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