Centenarians Alleviate Inflammaging by Changing the Ratio and Secretory Phenotypes of T Helper 17 and Regulatory T Cells

Centenarians Alleviate Inflammaging by Changing the Ratio and Secretory Phenotypes of T Helper 17 and Regulatory T Cells

The immune system of centenarians remains active and young to prevent cancer and infections. Aging is associated with inflammaging, a persistent low-grade inflammatory state in which CD4+ T cells play a role. However, there are few studies that have been done on the CD4+ T cell subsets in centenaria...

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Bibliographic Details
Main Authors: Lixing Zhou, Meiling Ge, Yan Zhang, Xiaochu Wu, Mi Leng, Chunmei Gan, Yi Mou, Jiao Zhou, C Alexander Valencia, Qiukui Hao, Bin Zhu, Biao Dong, Birong Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
centenarians
inflammaging
T helper 17 cell
regulatory T cell
aging
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.877709/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.877709/full

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