Characterizing modifications to a comparative effectiveness research study: the OPTIMIZE trial—using the Framework for Reporting Adaptations and Modifications to Evidence-based Interventions (FRAME)

Characterizing modifications to a comparative effectiveness research study: the OPTIMIZE trial—using the Framework for Reporting Adaptations and Modifications to Evidence-based Interventions (FRAME)

Abstract Background The OPTIMIZE trial is a multi-site, comparative effectiveness research (CER) study that uses a Sequential Multiple Assessment Randomized Trial (SMART) designed to examine the effectiveness of complex health interventions (cognitive behavioral therapy, physical therapy, and mindfu...

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Bibliographic Details
Main Authors: Julie M. Fritz, Tom Greene, Gerard P. Brennan, Kate Minick, Elizabeth Lane, Stephen T. Wegener, Richard L. Skolasky
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Trials
Subjects:
Comparative effectiveness research
Pragmatic clinical trial
Low back pain
Modification
Fidelity
Implementation
Online Access:https://doi.org/10.1186/s13063-023-07150-1

Internet

https://doi.org/10.1186/s13063-023-07150-1

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