Aberrantly elevated suprabasin in the bone marrow as a candidate biomarker of advanced disease state in myelodysplastic syndromes

Aberrantly elevated suprabasin in the bone marrow as a candidate biomarker of advanced disease state in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are preleukemic disorders characterized by clonal growth of mutant hematopoietic stem and progenitor cells. MDS are associated with proinflammatory signaling, dysregulated immune response, and cell death in the bone marrow (BM). Aging, autoinflammation and autoimmunit...

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Dades bibliogràfiques
Autors principals: Miroslav Pribyl, Sona Hubackova, Alena Moudra, Marketa Vancurova, Helena Polackova, Tomas Stopka, Anna Jonasova, Radka Bokorova, Ota Fuchs, Jan Stritesky, Barbora Salovska, Jiri Bartek, Zdenek Hodny
Format: Article
Idioma:English
Publicat: Wiley 2020-10-01
Col·lecció:Molecular Oncology
Matèries:
5‐azacytidine
biomarker
MDS
MDSCs
suprabasin
Accés en línia:https://doi.org/10.1002/1878-0261.12768

Internet

https://doi.org/10.1002/1878-0261.12768

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