Bilayered scaffold with 3D printed stiff subchondral bony compartment to provide constant mechanical support for long-term cartilage regeneration

Bilayered scaffold with 3D printed stiff subchondral bony compartment to provide constant mechanical support for long-term cartilage regeneration

Background/Objective: We seek to figure out the effect of stable and powerful mechanical microenvironment provided by Ti alloy as a part of subchondral bone scaffold on long-term cartilage regeneration.Methods: we developed a bilayered osteochondral scaffold based on the assumption that a stiff subc...

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Bibliographic Details
Main Authors: Tao Yang, Maryam Tamaddon, Le Jiang, Jing Wang, Ziyu Liu, Zhongqun Liu, Haoye Meng, Yongqiang Hu, Jianming Gao, Xuan Yang, Yanxu Zhao, Yanling Wang, Aiyuan Wang, Qiong Wu, Chaozong Liu, Jiang Peng, Xiaodan Sun, Qingyun Xue
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of Orthopaedic Translation
Subjects:
Bilayered scaffold
Osteochondral repair
Long-term cartilage repair
Biomechanical microenvironment
3D printing
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X21000681

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http://www.sciencedirect.com/science/article/pii/S2214031X21000681

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