PICALM rs3851179 Variants Modulate Left Postcentral Cortex Thickness, CSF Amyloid β42, and Phosphorylated Tau in the Elderly

PICALM rs3851179 Variants Modulate Left Postcentral Cortex Thickness, CSF Amyloid β42, and Phosphorylated Tau in the Elderly

PICALM rs3851179, one of the genes most frequently linked to susceptibility of late-onset Alzheimer’s disease (LOAD), plays a crucial role in regulating amyloid precursor protein, and amyloid β (Aβ) transcytosis. To explore the effects of PICALM and AD continuum stage on cortex thickness, CSF Aβ, an...

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Bibliographic Details
Main Authors: Zhiwei Wu, Yiwen Yang, Ziyang Song, Mengya Ma, Mengmeng Feng, Yuanqing Liu, Hanqi Xing, Yue Chang, Hui Dai
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Brain Sciences
Subjects:
Alzheimer’s disease
PICALM
rs3851179
amyloid β
phosphorylated tau
Online Access:https://www.mdpi.com/2076-3425/12/12/1681

Internet

https://www.mdpi.com/2076-3425/12/12/1681

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