Dual Knockdown of Musashi RNA-Binding Proteins MSI-1 and MSI-2 Attenuates Putative Cancer Stem Cell Characteristics and Therapy Resistance in Ovarian Cancer Cells

Dual Knockdown of Musashi RNA-Binding Proteins MSI-1 and MSI-2 Attenuates Putative Cancer Stem Cell Characteristics and Therapy Resistance in Ovarian Cancer Cells

In ovarian cancer, therapy resistance mechanisms complicate cancer cell eradication. Targeting Musashi RNA-binding proteins (MSI) may increase therapeutic efficacy. Database analyses were performed to identify gene expression associations between MSI proteins and key therapy resistance and cancer st...

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Bibliographic Details
Main Authors: Maria T. Löblein, Isabel Falke, Hans Theodor Eich, Burkhard Greve, Martin Götte, Fabian M. Troschel
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
ovarian cancer
therapy resistance
cancer stem cell
Musashi
radioresistance
notch
Online Access:https://www.mdpi.com/1422-0067/22/21/11502

Internet

https://www.mdpi.com/1422-0067/22/21/11502

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