Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils

Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils

The loss of inhibitor of differentiation-2 (ID2) could lead to the development of colitis in mice, supplementation with exogenous ID2 protein might be a potential strategy to ameliorate colitis. In this study, the effects of ID2 protein supplementation on Dextran sodium sulfate (DSS)-induced colitis...

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Bibliographic Details
Main Authors: Jie Ren, Dong Yan, Yichun Wang, Jiaojiao Zhang, Min Li, Wancheng Xiong, Xueqian Jing, Puze Li, Weidong Zhao, Xiwen Xiong, Minna Wu, Genshen Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
Inhibitor of differentiation-2 (ID2)
ulcerative colitis (UC)
intestinal barrier
neutrophils
nuclear factor kappa B (NF-κB)
recombinant protein
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.760999/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.760999/full

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