Reduced urine volume and changed renal sphingolipid metabolism in P2ry14-deficient mice

Reduced urine volume and changed renal sphingolipid metabolism in P2ry14-deficient mice

The UDP-glucose receptor P2RY14, a rhodopsin-like G protein-coupled receptor (GPCR), was previously described as receptor expressed in A-intercalated cells of the mouse kidney. Additionally, we found P2RY14 is abundantly expressed in mouse renal collecting duct principal cells of the papilla and epi...

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Bibliographic Details
Main Authors: Fabian Baalmann, Jana Brendler, Anne Butthof, Yulia Popkova, Kathrin M. Engel, Jürgen Schiller, Karsten Winter, Vera Lede, Albert Ricken, Torsten Schöneberg, Angela Schulz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
P2RY14
kidney
papilla
intercalated cells
aquaporin-2
sphingolipids
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1128456/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1128456/full

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