The function and clinical implication of YTHDF1 in the human system development and cancer

Abstract YTHDF1 is a well-characterized m6A reader protein that is essential for protein translation, stem cell self-renewal, and embryonic development. YTHDF1 regulates target gene expression by diverse molecular mechanisms, such as promoting protein translation or modulating the stability of mRNA....

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Bibliographic Details
Main Authors: Wenjun Ren, Yixiao Yuan, Yongwu Li, Luciano Mutti, Jun Peng, Xiulin Jiang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-023-00452-1