Wholegrain fermentation affects gut microbiota composition, phenolic acid metabolism and pancreatic beta cell function in a rodent model of type 2 diabetes

Wholegrain fermentation affects gut microbiota composition, phenolic acid metabolism and pancreatic beta cell function in a rodent model of type 2 diabetes

The intestinal microbiota plays an important role in host metabolism via production of dietary metabolites. Microbiota imbalances are linked to type 2 diabetes (T2D), but dietary modification of the microbiota may promote glycemic control. Using a rodent model of T2D and an in vitro gut model system...

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Bibliographic Details
Main Authors: Adele Costabile, Giulia Corona, Kittiwadee Sarnsamak, Daphna Atar-Zwillenberg, Chesda Yit, Aileen J. King, David Vauzour, Monica Barone, Silvia Turroni, Patrizia Brigidi, Astrid C. Hauge-Evans
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Microbiology
Subjects:
wholegrain
microbiota
polyphenols
pancreatic beta cells
type 2 diabetes
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1004679/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1004679/full

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