HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles

Bauzá-Martinez et al. analyzed the HLA-I peptide ligandome in extracellular vesicles (EVs) from an EBV-immortalized B cell line, JY, and compare HLA-I-binding peptides recovered from EVs to those recovered from whole-cells. The authors report an enrichment for HLA-B-binding peptides and for post-tra...

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Bibliographic Details
Main Authors: Julia Bauzá-Martinez, Albert J. R. Heck, Wei Wu
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02364-y