In Silico Substrate-Binding Profiling for SARS-CoV-2 Main Protease (M<sup>pro</sup>) Using Hexapeptide Substrates
The SARS-CoV-2 main protease (M<sup>pro</sup>) is essential for the life cycle of the COVID-19 virus. It cleaves the two polyproteins at 11 positions to generate mature proteins for virion formation. The cleavage site on these polyproteins is known to be Leu-Gln↓(Ser/Ala/Gly). A range of...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-06-01
|
| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/15/7/1480 |