A New Method for Improving Extraction Efficiency and Purity of Urine and Plasma Cell-Free DNA

A New Method for Improving Extraction Efficiency and Purity of Urine and Plasma Cell-Free DNA

This study assessed three commercially available cell-free DNA (cfDNA) extraction kits and the impact of a PEG-based DNA cleanup procedure (DNApure) on cfDNA quality and yield. Six normal donor urine and plasma samples and specimens from four pregnant (PG) women carrying male fetuses underwent extra...

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Bibliographic Details
Main Authors: Selena Y. Lin, Yue Luo, Matthew M. Marshall, Barbara J. Johnson, Sung R. Park, Zhili Wang, Ying-Hsiu Su
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Diagnostics
Subjects:
cell-free DNA
biospecimen variability
liquid biopsy
plasma
urine
precision medicine
Online Access:https://www.mdpi.com/2075-4418/11/4/650

Internet

https://www.mdpi.com/2075-4418/11/4/650

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