Prolyl-4-Hydroxylase 2 Potentially Contributes to Hepatocellular Carcinoma-Associated Erythrocytosis by Maintaining Hepatocyte Nuclear Factor-4α Expression

Prolyl-4-Hydroxylase 2 Potentially Contributes to Hepatocellular Carcinoma-Associated Erythrocytosis by Maintaining Hepatocyte Nuclear Factor-4α Expression

Background: Increased red blood cell count (Erythrocytosis) is an important paraneoplastic syndrome of hepatocellular carcinoma (HCC) and is a significant risk factor for lethal lung artery thromboembolism. HCC-associated erythrocytosis is partially caused by the ability of several HCC cells to prod...

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Bibliographic Details
Main Authors: Wenwen Sun, Friederike Katharina Kosyna, Wolfgang Jelkmann, Reinhard Depping
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Erythropoietin
HCC
HNF
Online Access:http://www.karger.com/Article/FullText/438581

Internet

http://www.karger.com/Article/FullText/438581

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