Bryonolic Acid Blocks Cancer Cell Clonogenicity and Invasiveness through the Inhibition of Fatty Acid: Cholesteryl Ester Formation
Bryonolic acid (BrA) is a pentacyclic triterpene present in several plants used in African traditional medicine such as Anisophyllea dichostyla R. Br. Here we investigated the in vitro anticancer properties of BrA. We report that BrA inhibits acyl-coA: cholesterol acyl transferase (ACAT) activity in...
Main Authors: | Farid Khallouki, Robert Wyn Owen, Sandrine Silvente-Poirot, Marc Poirot |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-02-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | http://www.mdpi.com/2227-9059/6/1/21 |
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