Development of a rapid electrophoretic assay for genomic DNA damage quantification

Development of a rapid electrophoretic assay for genomic DNA damage quantification

Accuracy, sensitivity, simplicity, reproducibility, and low-cost are desirable requirements for genotoxicity assessment techniques. Here we describe a simple electrophoretic assay for genomic DNA lesions quantification (EAsy-GeL) based on subjecting DNA samples to rapid unwinding/renaturation treatm...

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Bibliographic Details
Main Authors: James Eduardo Lago Londero, Cassiano Ricardo Schavinski, Fernanda D'Avila da Silva, Bruna Candia Piccoli, André Passaglia Schuch
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
DNA lesion
DNA repair
Genotoxicity testing
DNA breaks
Alkaline unwinding
DNA repair enzymes
Online Access:http://www.sciencedirect.com/science/article/pii/S014765132031695X

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http://www.sciencedirect.com/science/article/pii/S014765132031695X

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