An early-onset specific polygenic risk score optimizes age-based risk estimate and stratification of prostate cancer: population-based cohort study
Abstract Background Early-onset prostate cancer (EOPC, ≤ 55 years) has a unique clinical entity harboring high genetic risk, but the majority of EOPC patients still substantial opportunity to be early-detected thus suffering an unfavorable prognosis. A refined understanding of age-based polygenic ri...
Główni autorzy: | , , , , , , , , , |
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Format: | Artykuł |
Język: | English |
Wydane: |
BMC
2024-04-01
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Seria: | Journal of Translational Medicine |
Hasła przedmiotowe: | |
Dostęp online: | https://doi.org/10.1186/s12967-024-05190-y |