Single-molecule tracking (SMT) and localization of SRF and MRTF transcription factors during neuronal stimulation and differentiation

Single-molecule tracking (SMT) and localization of SRF and MRTF transcription factors during neuronal stimulation and differentiation

In cells, proteins encoded by the same gene do not all behave uniformly but engage in functional subpopulations induced by spatial or temporal segregation. While conventional microscopy has limitations in revealing such spatial and temporal diversity, single-molecule tracking (SMT) microscopy circum...

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Bibliographic Details
Main Authors: Oliver Kuchler, Jule Gerlach, Thomas Vomhof, Johannes Hettich, Julia Steinmetz, J. Christof M. Gebhardt, Jens Michaelis, Bernd Knöll
Format: Article
Language:English
Published: The Royal Society 2022-05-01
Series:Open Biology
Subjects:
SRF
MRTF
snap-tag
halo-tag
single-molecule
transcription
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.210383

Internet

https://royalsocietypublishing.org/doi/10.1098/rsob.210383

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