Synthesis of New Pyrazolo[3,4-<i>d</i>]pyrimidine Derivatives: NMR Spectroscopic Characterization, X-Ray, Hirshfeld Surface Analysis, DFT, Molecular Docking, and Antiproliferative Activity Investigations
Four new pyrazolo[3,4-<i>d</i>]pyrimidines (<b>P1</b>–<b>P4</b>) were successfully synthesized in good relative yields by reacting 3-methyl-1-phenyl-1H-pyrazolo[3,4-<i>d</i>]pyrimidin-4-ol with various alkylating agents (methyl iodide, propargyl bromid...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-10-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/29/21/5020 |