Proximal tubular transport of Metallothionein-Mercury complexes and protection against nephrotoxicity

Proximal tubular transport of Metallothionein-Mercury complexes and protection against nephrotoxicity

Mercury (Hg) is an important environmental toxicant to which humans are exposed on a regular basis. Mercuric ions within biological systems do not exist as free ions. Rather, they are bound to free sulfhydryl groups (thiols) on biological molecules. Metallothionein (MT) is a cysteine-rich, metal-bin...

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Bibliographic Details
Main Authors: Aditi Dave, Lucy Joshee, Delon W. Barfuss, Ryan Brownlee, Roha Surani, Sahar Anis Ali, Earl G. Ford IV, Elizabeth G. Pittman, Anasalea V.G. Caroland, Jennifer Barkin, Christy C. Bridges
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Toxicology
Subjects:
Mercury
Metallothionein
Kidney
Nephrotoxicity
Heavy metals
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X23000300

Internet

http://www.sciencedirect.com/science/article/pii/S2666027X23000300

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