MSIsensor-pro: Fast, Accurate, and Matched-normal-sample-free Detection of Microsatellite Instability

MSIsensor-pro: Fast, Accurate, and Matched-normal-sample-free Detection of Microsatellite Instability

Microsatellite instability (MSI) is a key biomarker for cancer therapy and prognosis. Traditional experimental assays are laborious and time-consuming, and next-generation sequencing-based computational methods do not work on leukemia samples, paraffin-embedded samples, or patient-derived xenografts...

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Bibliographic Details
Main Authors: Peng Jia, Xiaofei Yang, Li Guo, Bowen Liu, Jiadong Lin, Hao Liang, Jianyong Sun, Chengsheng Zhang, Kai Ye
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Microsatellite
Polymerase slippage
Multinomial distribution
Microsatellite instability
Tumor
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022920300218

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http://www.sciencedirect.com/science/article/pii/S1672022920300218

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