Cytotoxic effects of ivermectin on Giardia lamblia: induction of apoptosis and cell cycle arrest

Cytotoxic effects of ivermectin on Giardia lamblia: induction of apoptosis and cell cycle arrest

IntroductionGiardia lamblia is a flagellated protozoan parasite causing giardiasis, a common intestinal infection characterized by diarrhea, abdominal cramps, and nausea. Treatments employed to combat this parasitic infection have remained unchanged for the past 40 years, leading to the emergence of...

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Bibliographic Details
Main Authors: Florencia Nicole Barzola, Jerónimo Laiolo, Camilo Cotelo, Mariana Belén Joray, Ximena Volpini, María Romina Rivero, Andrea Silvana Rópolo, María Carolina Touz, Constanza Feliziani
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Microbiology
Subjects:
ivermectin
parasitic infections
cytotoxicity
apoptosis
necrosis
anti-giardial agent
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1484805/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2024.1484805/full

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