The pro-differentiating capability of a flavonoid-rich extract of Citrus bergamia juice prompts autophagic death in THP-1 cells

The pro-differentiating capability of a flavonoid-rich extract of Citrus bergamia juice prompts autophagic death in THP-1 cells

Abstract Acute myeloid leukemia (AML) is a hematologic neoplasm, characterized by a blockage of differentiation and an unconstrained proliferation of immature myeloid cells. Recently, the survival of leukemia patients has increased thanks to the use of differentiating agents, though these may cause...

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Bibliographic Details
Main Authors: Laura Musumeci, Caterina Russo, Udo Schumacher, Giovanni Enrico Lombardo, Alessandro Maugeri, Michele Navarra
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Scientific Reports
Subjects:
Acute myeloid leukemia
Bergamot juice extract
Flavonoids
Nutraceuticals
Differentiation
Autophagy
Online Access:https://doi.org/10.1038/s41598-024-70656-4

Internet

https://doi.org/10.1038/s41598-024-70656-4

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