Plasmacytoid Dendritic Cells as a New Therapeutic Target for Autoimmune Pancreatitis and IgG4-Related Disease

Plasmacytoid Dendritic Cells as a New Therapeutic Target for Autoimmune Pancreatitis and IgG4-Related Disease

Although plasmacytoid dendritic cells (pDCs) able to produce large amounts of type 1 interferons (IFN-I) play beneficial roles in host defense against viral infections, excessive activation of pDCs, followed by robust production of IFN-I, causes autoimmune disorders including systemic lupus erythema...

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Bibliographic Details
Main Authors: Kosuke Minaga, Tomohiro Watanabe, Akane Hara, Tomoe Yoshikawa, Ken Kamata, Masatoshi Kudo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
autoimmune pancreatitis
IgG4-related disease
plasmacytoid dendritic cells
interferon-I
interleukin-33
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.713779/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.713779/full

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