Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway

Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway

Abstract Background Glioblastomas are lethal brain tumors under the current combinatorial therapeutic strategy that includes surgery, chemo- and radio-therapies. Extensive changes in the tumor microenvironment is a key reason for resistance to chemo- or radio-therapy and frequent tumor recurrences....

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Bibliographic Details
Main Authors: Jiabin Pan, Shiyang Sheng, Ling Ye, Xiaonan Xu, Yizhao Ma, Xuanran Feng, Lisha Qiu, Zhaohuan Fan, Yi Wang, Xiaohuan Xia, Jialin C. Zheng
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Cell Communication and Signaling
Subjects:
Glioblastoma
Extracellular vesicles
Neural progenitor cells
Proliferation
Migration
PI3K
Online Access:https://doi.org/10.1186/s12964-021-00760-9

Internet

https://doi.org/10.1186/s12964-021-00760-9

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