Altered protein dynamics of disease-associated lamin A mutants

<p>Abstract</p> <p>Background</p> <p>Recent interest in the function of the nuclear lamina has been provoked by the discovery of lamin A/C mutations in the laminopathy diseases. However, it is not understood why mutations in lamin A give such a range of tissue-specific...

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Bibliographic Details
Main Authors: Worman Howard J, Östlund Cecilia, Perry Paul, Gilbert Nick, Gilchrist Susan, Bickmore Wendy A
Format: Article
Language:English
Published: BMC 2004-12-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/5/46