CpG-Activated Regulatory B-Cell Progenitors Alleviate Murine Graft-Versus-Host-Disease

CpG-Activated Regulatory B-Cell Progenitors Alleviate Murine Graft-Versus-Host-Disease

Development of Graft Versus Host Disease (GVHD) represents a major impediment in allogeneic hematopoietic stem cell transplantation (HSCT). The observation that the presence of bone marrow and circulating hematogones correlated with reduced GVHD risks prompted us to evaluate whether B-cell progenito...

Full description

Bibliographic Details
Main Authors: Viviane A. Agbogan, Pauline Gastineau, Emmanuel Tejerina, Saoussen Karray, Flora Zavala
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
allogeneic stem cell transplantation (allo-SCT)
regulatory B-cell progenitors
CpG-proBs
cell therapy
fibrosis
Bregs: regulatory B cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.790564/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.790564/full

Similar Items