CpG-Activated Regulatory B-Cell Progenitors Alleviate Murine Graft-Versus-Host-Disease

CpG-Activated Regulatory B-Cell Progenitors Alleviate Murine Graft-Versus-Host-Disease

Development of Graft Versus Host Disease (GVHD) represents a major impediment in allogeneic hematopoietic stem cell transplantation (HSCT). The observation that the presence of bone marrow and circulating hematogones correlated with reduced GVHD risks prompted us to evaluate whether B-cell progenito...

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Bibliographic Details
Main Authors:	Viviane A. Agbogan, Pauline Gastineau, Emmanuel Tejerina, Saoussen Karray, Flora Zavala
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-04-01
Series:	Frontiers in Immunology
Subjects:	allogeneic stem cell transplantation (allo-SCT) regulatory B-cell progenitors CpG-proBs cell therapy fibrosis Bregs: regulatory B cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.790564/full

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