Divergent synthesis of chiral cyclic azides via asymmetric cycloaddition reactions of vinyl azides

Vinyl azides generally act as 3-atom synthon through the fast release of molecular nitrogen, whereas keeping the azide group intact is more challenging. Here, the authors show a copper-catalyzed enantioselective cycloaddition of two types of vinyl azides generating a diverse pool of valuable chiral...

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Bibliographic Details
Main Authors: Nuligonda Thirupathi, Fang Wei, Chen-Ho Tung, Zhenghu Xu
Format: Article
Language:English
Published: Nature Portfolio 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11134-8