The Specificity of ParR Binding Determines the Incompatibility of Conjugative Plasmids in Clostridium perfringens

The Specificity of ParR Binding Determines the Incompatibility of Conjugative Plasmids in Clostridium perfringens

ABSTRACT Plasmids that encode the same replication machinery are generally unable to coexist in the same bacterial cell. However, Clostridium perfringens strains often carry multiple conjugative toxin or antibiotic resistance plasmids that are closely related and encode similar Rep proteins. In many...

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Bibliographic Details
Main Authors: Thomas D. Watts, Daouda A. K. Traore, Sarah C. Atkinson, Carmen Lao, Natalie Caltabiano, Julian I. Rood, Vicki Adams
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:mBio
Subjects:
plasmid partitioning
plasmid maintenance
plasmid incompatibility
Clostridium perfringens
ParR
parC
Online Access:https://journals.asm.org/doi/10.1128/mbio.01356-22

Internet

https://journals.asm.org/doi/10.1128/mbio.01356-22

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