The Progestin Medroxyprogesterone Acetate Affects HIV-1 Production in Human Lymphoid Tissue Explants in a Dose-Dependent and Glucocorticoid-like Fashion

The Progestin Medroxyprogesterone Acetate Affects HIV-1 Production in Human Lymphoid Tissue Explants in a Dose-Dependent and Glucocorticoid-like Fashion

The association between the use of the injectable contraceptive depot medroxyprogesterone acetate and HIV-1 susceptibility has been addressed mainly in respect to the changes occurring in the female genital mucosa and blood. However, one of the main sites of HIV-1 pathogenesis is lymphoid organs. To...

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Bibliographic Details
Main Authors: Christophe Vanpouille, Gökçe Günaydın, Mattias Jangard, Mario Clerici, Leonid Margolis, Kristina Broliden, Andrea Introini
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Viruses
Subjects:
hormonal contraception
sex hormones
progesterone
DMPA
glucocorticoids
HIV-1
Online Access:https://www.mdpi.com/1999-4915/13/11/2303

Internet

https://www.mdpi.com/1999-4915/13/11/2303

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