Pathogenesis of Atopic Dermatitis: Current Paradigm

Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized. Clinical efficacy of the anti-IL-4 receptor antibody dupilumab implies that type 2 cytokines IL-4 and IL-13 have pivotal r...

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Bibliographic Details
Main Authors: Masutaka Furue, Dugarmaa Ulzii, Yen Vu, Gaku Tsuji, Makiko Kido-Nakahara, Takeshi Nakahara
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2019-06-01
Series:Iranian Journal of Immunology
Subjects:
Online Access:https://iji.sums.ac.ir/article_44935_c53608540ed3579a71fb27ceee4a5e68.pdf