Immune Landscape of the Tumor Microenvironment Identifies Prognostic Gene Signature CD4/CD68/CSF1R in Osteosarcoma

Immune Landscape of the Tumor Microenvironment Identifies Prognostic Gene Signature CD4/CD68/CSF1R in Osteosarcoma

Background: Osteosarcoma (OSA), the most common primary bone malignancy in children and adolescents, is prone to metastases and unfavorable prognosis. Owing to its strong genomic heterogeneity, traditional chemotherapy, or targeted immunotherapy has not effectively improved the related overall survi...

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Bibliographic Details
Main Authors: Yi-jiang Song, Yanyang Xu, Xiaojun Zhu, Jianchang Fu, Chuangzhong Deng, Hongmin Chen, Huaiyuan Xu, Guohui Song, Jinchang Lu, Qinglian Tang, Jin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
osteosarcoma
tumor immune microenvironment
prognostic gene signature
tumor infiltrating immune cells
tumor-associated macrophages
tumor-infiltrating lymphocytes
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01198/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01198/full

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