Both indirect maternal and direct fetal genetic effects reflect the observational relationship between higher birth weight and lower adult bone mass

Both indirect maternal and direct fetal genetic effects reflect the observational relationship between higher birth weight and lower adult bone mass

Abstract Background Birth weight is considered not only to undermine future growth, but also to induce lifelong diseases; the aim of this study is to explore the relationship between birth weight and adult bone mass. Methods We performed multivariable regression analyses to assess the association of...

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Bibliographic Details
Main Authors: Jiang-Wei Xia, Lin Zhang, Jin Li, Cheng-Da Yuan, Xiao-Wei Zhu, Yu Qian, Saber Khederzadeh, Jia-Xuan Gu, Lin Xu, Jian-Hua Gao, Ke-Qi Liu, David Karasik, Shu-Yang Xie, Guo-Bo Chen, Hou-Feng Zheng
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Medicine
Subjects:
Birth weight
Bone mineral density
Fetal genetic effects
Maternal genetic effects
Observational analysis
Mendelian randomization
Online Access:https://doi.org/10.1186/s12916-022-02531-w

Internet

https://doi.org/10.1186/s12916-022-02531-w

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