Genome-wide Identification and Analysis of Splicing QTLs in Multiple Sclerosis by RNA-Seq Data

Genome-wide Identification and Analysis of Splicing QTLs in Multiple Sclerosis by RNA-Seq Data

Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory demyelinating lesions in the central nervous system. Recently, the dysregulation of alternative splicing (AS) in the brain has been found to significantly influence the progression of MS. Moreover, previous studies demons...

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Bibliographic Details
Main Authors: Yijie He, Lin Huang, Yaqin Tang, Zeyuan Yang, Zhijie Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Genetics
Subjects:
multiple sclerosis
alternative splicing
RNA-seq
splicing quantitative trait loci
function analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.769804/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.769804/full

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