Deletion patterns, genetic variability and protein structure of pfhrp2 and pfhrp3: implications for malaria rapid diagnostic test in Amhara region, Ethiopia

Deletion patterns, genetic variability and protein structure of pfhrp2 and pfhrp3: implications for malaria rapid diagnostic test in Amhara region, Ethiopia

Abstract Background Although rapid diagnostic tests (RDTs) play a key role in malaria-control strategies, their efficacy has been threatened by deletion and genetic variability of the genes pfhrp2/3. This study aims to characterize the deletion, genetic patterns and diversity of these genes and thei...

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Bibliographic Details
Main Authors: Irene Molina - de la Fuente, Mulat Yimar, Luz García, Vicenta González, Arancha Amor, Melaku Anegagrie, Agustín Benito, Javier Martínez, Marta Moreno, Pedro Berzosa
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Malaria Journal
Subjects:
Malaria
Ethiopia
Plasmodium falciparum
pfhrp2
Rapid diagnostic test
Deletions
Online Access:https://doi.org/10.1186/s12936-022-04306-3

Internet

https://doi.org/10.1186/s12936-022-04306-3

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